Alumis Inc.

Alumis Inc. (ALMS) Market Cap

Alumis Inc. has a market capitalization of .

No quote data available.

CEO: Martin Babler

Sector: Healthcare

Industry: Biotechnology

IPO Date: 2024-06-28

Website: https://www.alumis.com

Alumis Inc. (ALMS) - Company Information

Market Cap: -|Sector: Healthcare

Company Profile

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases. It also develops lonigutamab, a monoclonal antibody targeting IGF-1R for the treatment of thyroid eye diseases; and interferon regulatory factor 5 (IRF5) to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. Alumis Inc. was incorporated in 2021 and is headquartered in South San Francisco, California.

Analyst Sentiment

82%
Strong Buy

From 11 Active Polls

1Y Forecast: $39.17

▲ +0.0% Potential Upside

Consensus Target Metrics

Low Bound

$25

Median

$40

High Bound

$51

Average

$39

Price & Moving Averages

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🎯 Wall Street Analyst Intelligence Report

1-Year structural target targets, chart projections, and sentiment maps.

Average 1Y Target
$39.17
▲ +38.65% Upside
Low Target
$25.00
-12% Risk
Median Target
$39.50
40% Mid
High Target
$51.00
81% Max

Consensus Trend Projection

Trailing closures vs. 12-month metrics map.

Analyst Vote Distribution

Aggregate institutional coverage sentiment weights.

Sentiment volume allocation data unavailable.

Historical valuation matrix unavailable.

📘 Full Research Report

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AI-Generated Research: This report is for informational purposes only.

📘 ALUMIS INC (ALMS) — Investment Overview

🧩 Business Model Overview

ALUMIS INC operates in the aluminum value chain as a manufacturer and processor of aluminum products for industrial and end-market customers. The core “how it works” is a production-to-customer workflow: incoming aluminum input (and related processing inputs) is transformed through proprietary processing steps into customer-specified products, followed by sales into qualified customer programs.

Because industrial customers require consistent quality, reliable supply, and repeatable processing performance, the business model naturally emphasizes product qualification, adherence to specifications, and ongoing production execution—factors that increase customer stickiness after initial onboarding.

💰 Revenue Streams & Monetisation Model

Revenue is primarily generated through the sale of aluminum products on contractual and purchase-order arrangements. Monetisation is driven by (1) volume throughput and (2) the net pricing achievable for processed products versus input costs.

Margin structure typically reflects:

  • Product mix and processing depth: higher-value downstream processing generally supports better gross margin profiles.
  • Manufacturing utilization: fixed costs are spread over higher volumes when production runs consistently.
  • Input-cost pass-through: where pricing mechanisms mitigate aluminum and energy/input volatility, earnings quality improves.

🧠 Competitive Advantages & Market Positioning

Competitive moat (structural): customer qualification switching costs combined with execution reliability in a tightly specified manufacturing environment.

Once a customer’s engineering, quality, and sourcing teams qualify materials and manufacturing processes, switching suppliers is costly and time-consuming. Competitors can sell similar material only after meeting qualification requirements, maintaining consistent quality, and supporting schedule reliability—creating a practical barrier beyond simple pricing.

  • ALUMIS positioning: focus on delivering processed aluminum products with production consistency and qualification-driven customer stickiness.
  • Competitor set: Novelis, Constellium, and Hydro (among the broader aluminum processing ecosystem).

Contrast vs. rivals: Novelis, Constellium, and Hydro tend to compete across wide aluminum processing categories and end markets, leveraging scale and product breadth. The practical differentiation for ALUMIS is less about absolute scale and more about qualification-driven customer retention, manufacturing execution, and the ability to sustain repeatable quality at the product level customers require.

🚀 Multi-Year Growth Drivers

Over a 5–10 year horizon, growth prospects for a specialized aluminum processor are typically supported by:

  • Ongoing lightweighting demand: aluminum substitutes for heavier materials in transportation and industrial applications where weight, corrosion resistance, and lifecycle performance matter.
  • End-market diversification: spreading exposure across multiple industrial demand streams reduces dependence on a single cycle.
  • Qualification “pull-through”: once programs are established, follow-on orders can extend customer relationships, supporting volume stability.
  • Process optimization: improvements in yield, scrap reduction, and throughput can drive margin expansion without requiring broad price increases.

TAM expansion is fundamentally tied to aluminum’s share gains in weight- and performance-sensitive applications and to the incremental complexity customers place on sourcing (quality, schedule certainty, and specification compliance).

⚠ Risk Factors to Monitor

  • Input-price and spread volatility: aluminum and related input costs can pressure margins if pricing mechanisms do not sufficiently offset volatility.
  • Capacity utilization risk: industrial manufacturing economics can deteriorate when demand weakens and fixed-cost absorption falls.
  • Customer concentration and program timing: changes in customer sourcing strategies, product redesigns, or program delays can affect volumes.
  • Execution and quality risk: failure to meet specification or delivery reliability can force requalification cycles and increase churn risk.
  • Regulatory and environmental compliance: manufacturing compliance costs and evolving environmental requirements can affect operating economics.

📊 Valuation & Market View

Industrial and materials-linked manufacturers are commonly valued on EV/EBITDA, enterprise value relative to earnings power, and cash flow durability, with sentiment often influenced by expectations for manufacturing utilization and input-cost pass-through.

Key valuation drivers typically include:

  • Normalized margins: sustained ability to convert throughput and mix into resilient gross profit.
  • Operating leverage: evidence that earnings improve with volume rather than merely through price cycles.
  • Working-capital discipline: inventory and receivables management that supports free cash flow through cycles.
  • Program longevity: visibility into customer qualification-driven order flow.

🔍 Investment Takeaway

ALUMIS INC’s long-term case rests on qualification-driven switching costs and the ability to sustain repeatable manufacturing execution in a specification-heavy aluminum processing environment. While results remain exposed to the industrial cycle and input-cost volatility, the strongest structural support for an evergreen thesis is the practical difficulty competitors face in displacing qualified suppliers once customer programs are established.


⚠ AI-generated — informational only. Validate using filings before investing.

📊 AI Financial Analysis

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Earnings Data: Q Ending 2026-03-31

"ALMS reported Q1’26 revenue of $1.74M and net income of -$93.1M (EPS -$0.74). On a QoQ basis, revenue fell from $1.93M in Q4’25 to $1.74M in Q1’26 (-9.8% QoQ). On a YoY basis, revenue was down sharply versus $17.39M in Q1’25 (-90.0% YoY). Net income remained deeply loss-making: -$93.1M in Q1’26 versus -$92.9M in Q4’25 (about flat QoQ, +0.1%) and versus -$98.96M in Q1’25 (improvement of +5.9% YoY). Profitability remains weak, with net margin at -53.4% in Q1’26; operating margin deteriorated versus Q4’25 (-43.8%) to -56.5%, consistent with margin contraction driven by very high R&D. Cash flow is pressured but largely offset by financing and investment flows. Operating cash flow was -$87.1M, while investing cash flow was -$285.7M, reflecting heavy purchases of investments. Despite this, financing cash flow was +$347.0M, driven by common stock issued (dilution). Balance sheet liquidity is still strong: cash & short-term investments were $522.9M at 2026-03-31, with net cash (net debt -$28.2M). No dividends were paid and there were no buybacks. From a shareholder returns perspective, the stock shows exceptional momentum (1Y change +392.9%), which should materially boost total return despite ongoing operating losses and negative free cash flow."

Revenue Growth

Neutral

Revenue declined -9.8% QoQ (from $1.93M to $1.74M) and -90.0% YoY (from $17.39M). Trajectory is sharply down.

Profitability

Neutral

Net income improved slightly YoY (-$98.96M to -$93.05M, +5.9% less loss) but QoQ was essentially flat. Margins remain highly negative: net margin -53.4% in Q1’26 vs -48.2% in Q4’25 (contraction).

Cash Flow Quality

Neutral

Operating cash flow was -$87.1M and free cash flow -$87.2M. No dividends/buybacks; financing via dilution (+$323.8M stock issued) helped offset cash burn.

Leverage & Balance Sheet

Positive

Liquidity remains strong with cash & short-term investments of $522.9M. Net debt is negative (net cash -$28.2M). Equity is positive though below recent highs due to heavy retained losses.

Shareholder Returns

Strong

Strong market momentum: 1Y price change +392.9% (no dividend). Total shareholder return likely dominated by capital appreciation.

Analyst Sentiment & Valuation

Fair

Price targets imply upside (consensus $38.44 vs $24.99 current) despite extreme losses and high valuation multiples relative to revenue/earnings.

Disclaimer:This analysis is AI-generated for informational purposes only. Accuracy is not guaranteed and this does not constitute financial advice.

Fundamentals Overview

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© 2026 Stock Market Info — Alumis Inc. (ALMS) Financial Profile